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Livres
Articles (96)
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Human Brain Activity Response to Fentanyl Imaged by Positron Emission Tomography

Firestone, Leonard L., Gyulai, Ferenc, Mintun, Mark, Adler, Lauri Jo, Urso, Katie, Winter, Peter M.

Journal:

Anesthesia & Analgesia

Année:

1996

Langue:

english

Fichier:

PDF, 2.11 MB

english, 1996

Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity

Christine T. Brew, Ida Aronchik, Karena Kosco, Jasmine McCammon, Leonard F. Bjeldanes, Gary L. Firestone

Journal:

International Journal of Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 338 KB

english, 2009

Ligand-independent activation of estrogen receptor function by 3,3′-diindolylmethane in human breast cancer cells

Jacques E. Riby, Grace H.F. Chang, Gary L. Firestone, Leonard F. Bjeldanes

Journal:

Biochemical Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 443 KB

english, 2000

Regional Brain Activity Changes Associated with Fentanyl Analgesia Elucidated by Positron Emission Tomography

Adler, Lauri J., Gyulai, Ferenc E., Diehl, David J., Mintun, Mark A., Winter, Peter M., Firestone, Leonard L.

Journal:

Anesthesia & Analgesia

Année:

1997

Langue:

english

Fichier:

PDF, 1.16 MB

english, 1997

A meta-analysis with examination of moderators of student cognition, affect, and learning outcomes while using serious educational games, serious games, and simulations

Lamb, Richard L., Annetta, Leonard, Firestone, Jonah

Journal:

Computers in Human Behavior

Année:

2017

Langue:

english

Fichier:

PDF, 773 KB

english, 2017

Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells

Joann Zhang, Jocelyn C. Hsu B.A., Matthew A. Kinseth B.A., Leonard F. Bjeldanes, Gary L. Firestone

Journal:

Cancer

Année:

2003

Langue:

english

Fichier:

PDF, 313 KB

english, 2003

Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells

Christine T. Brew, Ida Aronchik, Jocelyn C. Hsu, Joon-Ho Sheen, Robert B. Dickson, Leonard F. Bjeldanes, Gary L. Firestone

Journal:

International Journal of Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 968 KB

english, 2006

Haemodynamic effects of rocuronium bromide in adult cardiac surgical patients

Mark E. Hudson, Kenneth P. Rothfield, William C. Tullock, Leonard L. Firestone

Journal:

Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Année:

1998

Langue:

english

Fichier:

PDF, 334 KB

english, 1998

Platelet membrane fluidity individuals at risk for Alzheimer’s disease: a comparison of results from fluorescence spectroscopy and electron spin resonance spectroscopy

George S. Zubenko, Ursula Kopp, Tomoyoshi Seto, Leonard L. Firestone

Journal:

Psychopharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 85 KB

english, 1999

Use of positron emission tomography to measure brain activity responses to fentanyl analgesia

Jiro Kurata, Ferenc E. Gyulai, Leonard L. Firestone

Journal:

Current Pain and Headache Reports

Année:

1999

Langue:

english

Fichier:

PDF, 319 KB

english, 1999

3,3′-Diindolylmethane stimulates murine immune function in vitro and in vivo

Ling Xue, James J. Pestka, Maoxiang Li, Gary L. Firestone, Leonard F. Bjeldanes

Journal:

The Journal of Nutritional Biochemistry

Année:

2008

Langue:

english

Fichier:

PDF, 380 KB

english, 2008

DIM stimulates IFNγ gene expression in human breast cancer cells via the specific activation of JNK and p38 pathways

Xue, Ling, Firestone, Gary L, Bjeldanes, Leonard F

Journal:

Oncogene

Année:

2005

Langue:

english

Fichier:

PDF, 431 KB

english, 2005

Target protein interactions of indole-3-carbinol and the highly potent derivative 1-Benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling

Ida Aronchik, Tony Chen, Kathleen A. Durkin, Marshall S. Horwitz, Maria N. Preobrazhenskaya, Leonard F. Bjeldanes, Gary L. Firestone

Journal:

Molecular Carcinogenesis

Année:

2012

Langue:

english

Fichier:

PDF, 515 KB

english, 2012

Ligand-dependent effects of ethanol and diethylether at brain benzodiazepine receptors

Joseph J. Quinlan, Leonard L. Firestone

Journal:

Pharmacology Biochemistry and Behavior

Année:

1992

Langue:

english

Fichier:

PDF, 297 KB

english, 1992

Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein

Jocelyn C. Hsu, Anurupa Dev, Aimee Wing, Christine T. Brew, Leonard F. Bjeldanes, Gary L. Firestone

Journal:

Biochemical Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 622 KB

english, 2006

N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells

Sarah M. Jump, Jenny Kung, Richard Staub, Matthew A. Kinseth, Erin J. Cram, Larisa N. Yudina, Maria N. Preobrazhenskaya, Leonard F. Bjeldanes, Gary L. Firestone

Journal:

Biochemical Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 664 KB

english, 2008

3,3′-Diindolylmethane reduces levels of HIF-1α and HIF-1 activity in hypoxic cultured human cancer cells

Jacques E. Riby, Gary L. Firestone, Leonard F. Bjeldanes

Journal:

Biochemical Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 785 KB

english, 2008

3,3′-Diindolylmethane induces a G1 arrest in human prostate cancer cells irrespective of androgen receptor and p53 status

Omar I. Vivar, Chia-Lei Lin, Gary L. Firestone, Leonard F. Bjeldanes

Journal:

Biochemical Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 460 KB

english, 2009

1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells

Hanh H. Nguyen, Sergey N. Lavrenov, Shyam N. Sundar, David H.H. Nguyen, Min Tseng, Crystal N. Marconett, Jenny Kung, Richard E. Staub, Maria N. Preobrazhenskaya, Leonard F. Bjeldanes, Gary L. Fireston

Journal:

Chemico-Biological Interactions

Année:

2010

Langue:

english

Fichier:

PDF, 559 KB

english, 2010

Bcl-2 family-mediated apoptotic effects of 3,3′-diindolylmethane (DIM) in human breast cancer cells

Chibo Hong, Gary L. Firestone, Leonard F. Bjeldanes

Journal:

Biochemical Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 526 KB

english, 2002

Cytostatic and antiestrogenic effects of 2-(indol-3-ylmethyl)-3,3′-diindolylmethane, a major in vivo product of dietary indole-3-carbinol

Yu-Chen Chang, Jacques Riby, Grace H-F Chang, BaoCheng Peng, Gary Firestone, Leonard F. Bjeldanes

Journal:

Biochemical Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 531 KB

english, 1999

Preoperative risk models for minimally invasive coronary bypass: A preliminary study

Marco Zenati, Howard A. Cohen, Richard Holubkov, A.J. Conrad Smith, Arthur J. Boujoukos, John Caldwell, Leonard Firestone, Bartley P. Griffith

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Année:

1998

Langue:

english

Fichier:

PDF, 43 KB

english, 1998

Mice Lacking the Long Splice Variant of the γ2 Subunit of the GABAA Receptor Are More Sensitive to Benzodiazepines

Joseph J Quinlan, Leonard L Firestone, Gregg E Homanics

Journal:

Pharmacology Biochemistry and Behavior

Année:

2000

Langue:

english

Fichier:

PDF, 54 KB

english, 2000

Pharmacologic and Behavioral Responses of Inbred C57BL/6J and Strain 129/SvJ Mouse Lines

Gregg E Homanics, Joseph J Quinlan, Leonard L Firestone

Journal:

Pharmacology Biochemistry and Behavior

Année:

1999

Langue:

english

Fichier:

PDF, 70 KB

english, 1999

Neonatal heart transplantation

Susan Firestone, Leonard Firestone

Journal:

Seminars in Anesthesia, Perioperative Medicine and Pain

Année:

1995

Langue:

english

Fichier:

PDF, 992 KB

english, 1995

Future directions in transplantation

Leonard Firestone

Journal:

Seminars in Anesthesia, Perioperative Medicine and Pain

Année:

1995

Langue:

english

Fichier:

PDF, 97 KB

english, 1995

Staurosporine, a Protein Kinase Inhibitor, Increases the Intoxicating Potencies of Ethanol and Other n-Alkanols in Rana pipiens Tadpoles

Susan Firestone, Leonard L. Firestone

Journal:

Alcoholism: Clinical and Experimental Research

Année:

1995

Langue:

english

Fichier:

PDF, 399 KB

english, 1995

Lipid-dependent differential effects of stereoisomers of anesthetic alcohols

Leonard L Firestone, Andrew S Janoff, Keith W Miller

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1987

Langue:

english

Fichier:

PDF, 541 KB

english, 1987

Two pools of cholesterol in acetylcholine receptor-rich membranes from Torpedo

Wayne S. Leibel, Leonard L. Firestone, Dwight C. Legler, Leon M. Braswell, Keith W. Miller

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1987

Langue:

english

Fichier:

PDF, 917 KB

english, 1987

Halothane's effects on GABA-gated chloride flux in mice selectively bred for sensitivity or resistance to diazepam

Joseph J. Quinlan, Edward J. Gallaher, Leonard L. Firestone

Journal:

Brain Research

Année:

1993

Langue:

english

Fichier:

PDF, 483 KB

english, 1993

Safety and efficacy of intranasal ketamine for the treatment of breakthrough pain in patients with chronic pain: a randomized, double-blind, placebo-controlled, crossover study

Daniel B Carr, Leonidas C Goudas, William T Denman, Daniel Brookoff, Peter S Staats, Loralie Brennen, Geoff Green, Randi Albin, Douglas Hamilton, Mark C Rogers, Leonard Firestone, Philip T Lavin, Fred

Journal:

PAIN®

Année:

2004

Langue:

english

Fichier:

PDF, 163 KB

english, 2004

Effects of normal alcohols and isoflurane on lipid headgroup dynamics in nicotinic acetylcholine receptor-rich lipid vesicles

Tomoyoshi Seto, Leonard L Firestone

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2000

Langue:

english

Fichier:

PDF, 373 KB

english, 2000

Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the γ2 subunit of the γ-aminobutyrate type A receptor

Gregg E. Homanics, Neil L. Harrison, Joseph J. Quinlan, Matthew D. Krasowski, Caroline E.M. Rick, Angel L. de Blas, Ashok K. Mehta, Frank Kist, Robert M. Mihalek, Jerome J. Aul, Leonard L. Firestone

Journal:

Neuropharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 374 KB

english, 1999

A deficit of functional GABAA receptors in neurons of β3 subunit knockout mice

Matthew D Krasowski, Caroline E Rick, Neil L Harrison, Leonard L Firestone, Gregg E Homanics

Journal:

Neuroscience Letters

Année:

1998

Langue:

english

Fichier:

PDF, 225 KB

english, 1998

Pain processing during three levels of noxious stimulation produces differential patterns of central activity

Stuart W.G Derbyshire, Anthony K.P Jones, Ferenc Gyulai, Stuart Clark, David Townsend, Leonard L Firestone

Journal:

PAIN®

Année:

1997

Langue:

english

Fichier:

PDF, 2.29 MB

english, 1997

Anesthesia for living-related (lobar) lung transplantation

Joseph J. Quinlan, Thomas Gasior, Susan Firestone, Leonard L. Firestone

Journal:

Journal of Cardiothoracic and Vascular Anesthesia

Année:

1996

Langue:

english

Fichier:

PDF, 728 KB

english, 1996

Anaesthetic potencies of primary alkanols: implications for the molecular dimensions of the anaesthetic site

James K. Alifimoff, Leonard L. Firestone, Keith W. Miller

Journal:

British Journal of Pharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1989

NMR Study of Volatile Anesthetic Binding to Nicotinic Acetylcholine Receptors

Xu, Yan, Seto, Tomoyoshi, Tang, Pei, Firestone, Leonard

Journal:

Biophysical Journal

Année:

2000

Langue:

english

Fichier:

PDF, 136 KB

english, 2000

Morpheus in Calgary: Third International Conference on Molecular and Cellular Mechanisms of Anesthesia, University of Calgary, Calgary, Alberta, Canada. June 1984

Roger S. Brett, Leonard L. Firestone

Journal:

Trends in Pharmacological Sciences

Année:

1985

Langue:

english

Fichier:

PDF, 354 KB

english, 1985

Immediate effects of lung transplantation on right ventricular morphology and function in patients with variable degrees of pulmonary hypertension

William E. Katz, Thomas A. Gasior, Joseph J. Quinlan, Jason M. Lazar, Leonard Firestone, Bartley P. Griffith, John Gorcsan III

Journal:

Journal of the American College of Cardiology

Année:

1996

Langue:

english

Fichier:

PDF, 878 KB

english, 1996

Genetic dissection of the molecular target(s) of anesthetics with the gene knockout approach in mice

Gregg E. Homanics, Joseph J. Quinlan, Robert Mihalek, Leonard L. Firestone

Journal:

Toxicology Letters

Année:

1998

Langue:

english

Fichier:

PDF, 135 KB

english, 1998

Gender differences in patterns of cerebral activation during equal experience of painful laser stimulation

Stuart W.G. Derbyshire, Thomas E. Nichols, Leonard Firestone, David W. Townsend, Anthony K.P. Jones

Journal:

The Journal of Pain

Année:

2002

Langue:

english

Fichier:

PDF, 421 KB

english, 2002

General Anesthetic and Specific Effects of Ethanol on Acetylcholine Receptors

KEITH W. MILLER, LEONARD L. FIRESTONE AND, STUART A. FORMAN

Journal:

Annals of the New York Academy of Sciences

Année:

1987

Langue:

english

Fichier:

PDF, 918 KB

english, 1987

Halothane Requirement in Mice Selectively Bred for Sensitivity or Resistance to Diazepam

ANNE McCRAE, LEONARD FIRESTONE, EDWARD J. GALLAHER, PETER WINTER

Journal:

Annals of the New York Academy of Sciences

Année:

1991

Langue:

english

Fichier:

PDF, 156 KB

english, 1991

3,3′-Diindolylmethane rapidly and selectively inhibits hepatocyte growth factor/c-Met signaling in breast cancer cells

Nicastro, Holly L., Firestone, Gary L., Bjeldanes, Leonard F.

Journal:

The Journal of Nutritional Biochemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2013

Pilot Study: Effect of 3,3′-Diindolylmethane Supplements on Urinary Hormone Metabolites in Postmenopausal Women With a History of Early-Stage Breast Cancer

Dalessandri, Kathie M., Firestone, Gary L., Fitch, Mark D., Bradlow, H. Leon, Bjeldanes, Leonard F.

Journal:

Nutrition and Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 101 KB

english, 2004

Mice Devoid of γ -Aminobutyrate Type A Receptor β 3 Subunit have Epilepsy, Cleft Palate, and Hypersensitive Behavior

Gregg E. Homanics, Timothy M. DeLorey, Leonard L. Firestone, Joseph J. Quinlan, Adrian Handforth, Neil L. Harrison, Matthew D. Krasowski, Caroline E. M. Rick, Esa R. Korpi, Rikka Makela, Murray H. Bri

Journal:

Proceedings of the National Academy of Sciences

Année:

1997

Langue:

english

Fichier:

PDF, 1.58 MB

english, 1997

Attenuated Sensitivity to Neuroactive Steroids in γ -Aminobutyrate Type A Receptor Delta Subunit Knockout Mice

Robert M. Mihalek, Pradeep K. Banerjee, Esa R. Korpi, Joseph J. Quinlan, Leonard L. Firestone, Zhi-Ping Mi, Carl Lagenaur, Verena Tretter, Werner Sieghart, Stephan G. Anagnostaras, Jennifer R. Sage, M

Journal:

Proceedings of the National Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 1.27 MB

english, 1999

The Major Cyclic Trimeric Product of Indole-3-carbinol Is a Strong Agonist of the Estrogen Receptor Signaling Pathway †

Riby, Jacques E., Feng, Chunling, Chang, Yu-Chen, Schaldach, Charlene M., Firestone, Gary L., Bjeldanes, Leonard F.

Journal:

Biochemistry

Année:

2000

Langue:

english

Fichier:

PDF, 323 KB

english, 2000

Is agonist self-inhibition at the nicotinic acetylcholine receptor a nonspecific action?

Forman, Stuart A., Firestone, Leonard L., Miller, Keith W.

Journal:

Biochemistry

Année:

1987

Langue:

english

Fichier:

PDF, 1.03 MB

english, 1987